University of Texas at Arlington scientists have pinpointed an enzyme, IDO1, that flips the body’s cholesterol-processing machinery into chaos during inflammation.
By shutting this “off switch,” immune cells called macrophages regain their ability to soak up cholesterol, potentially stopping heart disease, diabetes, cancer, and more before they start. The team also fingered nitric oxide synthase as an accomplice, hinting at a two-pronged drug strategy that could revolutionize treatment for millions.
Off-Switch Enzyme Offers Cholesterol Control…