Seattle scientist shares Nobel Prize in medicine for work on the human immune system

A Seattle scientist was among three who won the Nobel Prize in medicine on Monday for their work on the human immune system.

The Nobel Prize in Physiology or Medicine 2025 was awarded to Mary E. Brunkow, Fred Ramsdell, and Shimon Sakaguchi “for their discoveries concerning peripheral immune tolerance.”

Brunkow, 64, is a senior program manager at the Institute for Systems Biology in Seattle, Ramsdell, 64, is a scientific adviser for Sonoma Biotherapeutics in San Francisco, and Dr. Sakaguchi, 74, is a distinguished professor at the Immunology Frontier Research Center at Osaka University in Japan…

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