Multi-Vehicle Crash on US 90 Near Highway 151 Leaves Two Fighting for Life

Two people were rushed to the hospital in critical condition Wednesday evening after a multi-vehicle crash tore through the interchange where US Highway 90 westbound meets State Highway 151 on San Antonio’s West Side, snarling traffic for miles during the peak commute.

The San Antonio Fire Department confirmed both patients were transported in critical condition following the wreck, according to KABB, which first reported the crash near Highway 90 westbound and Highway 151. The outlet’s report, published Thursday and updated the same afternoon, described it simply as a major crash involving multiple vehicles that caused significant delays through the area. Exact details on how many vehicles were involved and what triggered the pileup have not been released.

The crash lands in one of San Antonio’s most heavily traveled and heavily worked-on corridors. The station’s report on the interchange comes as ongoing roadwork complicates conditions nearby — Texas Department of Transportation traffic records show active guardrail repair at Highway 151 and Ingram Road and separate construction on US 90 at Old Highway 90 this month, work that can narrow lanes and disrupt normal traffic flow right where drivers are merging at highway speeds.

A Corridor With a History of Major Wrecks

This isn’t the first time this stretch has ground to a halt. Per the same account, a major collision in December 2025 on Highway 151 heading toward US 90 forced San Antonio police to shut down multiple lanes, with backups stretching all the way to Callaghan Road. The interchange linking US 90, Highway 151, and Loop 410 sees heavy commuter volume that makes any crash there prone to cascading delays…

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