Nightmare scenario comes true as Louisville suffers biggest Transfer portal loss yet

Louisville football’s nightmare scenario officially comes true as the Cardinals learn on New Year’s Day that their star running back Isaac Brown will enter the Transfer Portal. The true sophomore has been one of the best running backs in the nation for the past two years, and while this was expected for the Cards, it is still a massive gut punch.

Brown has been dominant through his two seasons with the Cards. He shattered multiple records in his freshman season, including rushing yards by a freshman, and went on to win ACC Rookie of the Year. The Miami native will join Duke Watson and Shaun Boykins Jr. in the portal, making it clear Brohm must try to keep star RB Keyjuan Brown.

BREAKING: Louisville star RB Isaac Brown is entering the @TransferPortal, sources tell @On3SportsThrough 2 seasons he’s totaled 2,057 rushing yards and 18 TDs (7.7 YPC)He immediately becomes one of the Top Players in the portalhttps://t.co/RlUbB6Fk7qpic.twitter.com/614PUfnIpE

— Hayes Fawcett (@Hayesfawcett3) January 1, 2026

Louisville football’s nightmare scenario comes true

Brown was one of the best running backs in the nation, as the former 3-star commit exceeded all expectations in his first two seasons with the Cardinals after he rushed for 2,057 yards and 18 touchdowns. He led the nation in yards per carry, averaging 7.7 over two seasons, including his true freshman season, when he carried 165 times for 1,173 rushing yards…

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