Seafood po-boys in Louisiana are a glorious, messy ritual, and you will want extra napkins before the first bite. Shrimp tumble out, oysters crackle, and buttered bread hugs the chaos like a loyal friend. This list takes you from New Orleans classics to Lafayette legends, all stacking seafood sky high. Come hungry, leave grinning, and maybe wear a shirt you do not mind baptizing in hot sauce.
Parkway Bakery & Tavern – New Orleans, Louisiana
Parkway is where you learn the sacred po-boy equation: hot bread, crisp seafood, tangy sauce, and joy. The shrimp are fried golden, piled so high you have to corral them back in with every bite. Ask for extra napkins and extra pickles, because you will need them.
There is history in these walls, and locals swear by the roast beef too, but seafood steals the show. The bread has that shatter you hear before you feel it, a crunch that keeps you chasing. Grab a bar stool, order a cold drink, and let the sandwich lean on your elbows.
Domilise’s Po-Boy & Bar – New Orleans, Louisiana
Domilise’s feels like your auntie runs the fryer and refuses to let you leave hungry. The oyster po-boy arrives stacked and singing, dotted with hot sauce like confetti. A bite delivers briny crunch, cool mayo, and bread that holds its dignity till the last crumb.
You stand in line with locals who know the drill, smiling because the smell alone feels like home. Order dressed, grab chips, and claim a corner table with napkins at the ready. It is simple and perfect, the kind of sandwich that stays in your memory longer than your lunch break.
Verti Marte – New Orleans, Louisiana
Verti Marte is that tiny, always-open corner shop where cravings at midnight turn legendary. The sandwiches are wild, seafood stacked with reckless kindness. Shrimp, catfish, or soft-shell crab get tucked into bread like a party you can hold…