March 11, 2026 – Cardiac resynchronization therapy with a defibrillator is a common treatment that uses an implanted device to help weakened or failing hearts beat more efficiently. While this therapy helps some people with rhythm disorders, others may see little to no improvement.
In search of additional treatment options, Sarasota Memorial’s Kolschowsky Research and Education Institute has joined an international clinical trial, SYNCHRONICITY, evaluating the safety and effectiveness of a new pacing approach for heart failure patients.
Sponsored by Boston Scientific and led locally by Sarasota Memorial cardiac electrophysiologist Antonio Moretta, MD, the study is designed to compare two different pacing approaches – the current standard method of implanting a pacing lead in a vein on the surface of the left lower chamber of the heart (left ventricle) to deliver heart failure therapy (Cardiac Resynchronization Therapy, also known as CRT) and an experimental approach called Left Bundle Branch Area Pacing or LBBAP. LBBAP involves implanting a lead in the left bundle branch area of the heart. While the lead is approved by the Food and Drug Administration (FDA) to be implanted in this area of the heart, it has not been approved for the treatment of heart failure…