Layoffs hit Zuckerberg and Chan’s philanthropy in Silicon Valley

The Chan Zuckerberg Initiative is laying off about 70 employees in Redwood City as the philanthropy founded by Meta CEO Mark Zuckerberg and Dr. Priscilla Chan restructures to focus more narrowly on artificial intelligence-driven biomedical research.

The layoffs, confirmed Wednesday by communications director Jane Packer, are part of an ongoing transition as CZI centers its work on Biohub, a network of research institutes aimed at accelerating discoveries in biology and medicine with a stated mission “to cure or prevent all disease.”

The shift began in 2024, when the organization moved to become science-focused and consolidated previously separate research entities into a single, unified science organization…

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