The 5 Worst U.S. Cities for Allergies in 2026, Ranked

If your allergies are already unbearable this spring, you’re not alone. More than 82 million Americans have itchy eyes, watery nose, and scratchy throat. There are a few things you can do before you start sneezing to get ahead of symptoms, like taking allergy meds every day, and keeping your house wiped down.

Allergies are worse in some cities than others, according to the Asthma and Allergy Foundation of America. Every year, they produce an Allergy Capitals report, which ranks the 100 most populated U.S. metro areas according to grass, tree, and weed pollen levels, which serves as the metrics for an overall score. These scores are based on:

  • Tree, grass, and weed pollen scores (how many days each city has high or very high pollen counts)
  • Over-the-counter allergy medicine use
  • Availability of board-certified allergists/immunologists

Here’s the Top five cities hit the hardest.

Greenville, South Carolina

Greenville is set in the foothills of the Blue Ridge Mountains and has forests of pine trees that spread clouds of yellow pollen dust on cars, homes, and sidewalks.

Allergy score: 93.9

Spokane, Washington

Alder, birch, and cedar trees are the main instigator in spring. Hot, dry summers allow pollen from Bermuda and Timothy grass to stay in the air longer. During fall, ragweed is prevalent. Some people are allergic to some but not all allergens…

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