MSU researchers receive $4M grant to study possible dementia triggers

GRAND RAPIDS, Mich. (WOOD) — Dementia and Alzheimer’s disease are a growing concern for future generations, and Michigan State University plans to use a $4 million grant to learn more about the debilitating diseases.

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The university announced Wednesday that researchers with the department of psychiatry and the Colleges of Osteopathic Medicine and Human Medicine received the grant from the National Institutes of Health .

Their goal is to study the relationship between Alzheimer’s disease and related dementia and three variables: vitamin D deficiency, gut microbial imbalance and inflammation.

“In humans, vitamin D supports immune function and regulates thousands of genes via the vitamin D receptor, which can be found on many tissues, organ systems and cells,” the university said in a statement .

“Cognitive decline is a natural part of aging, but vitamin D deficiency accelerates neuron cell death and progression … by producing inflammation and oxidative potential. Gut microbial imbalance, which also worsens with age, can accelerate Alzheimer’s disease and related dementia through the gut-brain axis.”

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