Several southbound lanes of the 405 Freeway were shut down for several hours following a multi-car crash near the Brentwood area early Wednesday morning.
The collision was reported just after 2 a.m. south of Getty Center Drive, according to the California Highway Patrol. A semi-truck and two other cars were involved.
Three people were taken to the hospital for their injuries. One of the injured lost a leg, the CHP said…