At approximately 3:30am on March 4th, 2026, California Highway Patrol and Los Angeles Fire Department personnel responded to a fatal traffic collision on northbound US-101 at the Interstate 405 interchange in Sherman Oaks.
Authorities reported a truck crashed into a guardrail, causing the driver to be ejected from the vehicle. The victim was pronounced deceased at the scene. The Los Angeles County Coroner’s Office was notified and responded to the location.
A SigAlert was issued as multiple lanes were closed for investigation and cleanup. At one point, only one lane remained open on northbound US-101, along with limited access from the 101 onto the northbound and southbound 405…