Scientists have created brain “ organoids ” for years, but there are limitations to the tiny, lab-grown cultures . One of the most frustrating issues is a lack of control over their design, which often limits an organoid’s functionality and use . Although researchers long suspected 3D-printing could offer a solution, the workaround has so far proven difficult and ineffective. A new production breakthrough, however, could solve the longstanding barrier, and one day offer new ways of exploring treatment for diseases such as Parkinson’s and Alzeheimer’s.
As detailed in the new issue of the journal Cell Stem Cell , University of Wisconsin-Madison researchers have developed a novel 3D-printing approach for creating cultures that grow and operate similar to brain tissue. While traditional 3D-printing involves layering “bio-ink” vertically like a cake, the team instead tasked their machine to print horizontally, as if playing dominoes.
Related: A ‘brain organoid’ biochip displayed serious voice recognition and math skills .]