Indiana vs. Alabama betting odds will have Hoosiers fans thinking of the semifinals

The Indiana Hoosiers officially have their opponent for their first game in the 2025 College Football Playoff. After a 34-24 win over Oklahoma, Alabama has punched its ticket to the Rose Bowl with the Hoosiers, and it should be an electrifying matchup.

In the first 12-team College Football Playoff in 2024, every 1-seed that received the first-round bye fell in their first game in the Quarterfinals. Indiana is hoping to change that trend, but it certainly won’t be easy. The Tide proved that even though they got down early against the Sooners, they could mount a comeback.

This won’t be an easy game for the Hoosiers, especially with so much time having not played; they may need to knock off some rust. However, Vegas oddsmakers seem to have faith in the Hoosies as they have given them a favorable opening line against the Crimson Tide.

Alabama vs. Indiana early odds, spread, and total

Odds provided by FanDuel Sportsbook

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