The Tuskegee Experiment is a dark chapter in American history that continues to evoke strong emotions and discussions. Conducted from 1932 to 1972, this study aimed to observe the natural progression of untreated syphilis in African American men in Alabama. Participants were misled, believing they were receiving free healthcare from the government, when in reality, they were denied proper treatment even after penicillin became the standard cure. This unethical study highlights the importance of informed consent and ethical standards in medical research. Why does the Tuskegee Experiment matter today? It serves as a stark reminder of the potential for abuse in medical research and the necessity for transparency and ethics in healthcare. Understanding this history is crucial in rebuilding trust between marginalized communities and the medical field. Let’s delve into 35 facts that shed light on this significant yet troubling episode.