The Tucson Police Department say an AMR ambulance and another car were involved in a crash near I-10 between Miracle Mile and Grant Road just before 2 a.m. Tuesday morning.
Two paramedics in the ambulance and the driver of the car are in critical condition.
UPDATE 6:52am the car was traveling the wrong way on I-10 near milepost 258 westbound in the eastbound lanes before colliding head on into the ambulance.
Stay with KGUN9 for updates.