Portland drivers heading south on I-5 this Thanksgiving should plan carefully to avoid major delays. According to INRIX, the worst travel times are expected on Tuesday, November 26th, from 1:00 PM to 7:00 PM, with traffic congestion significantly higher than normal. Travelers on Wednesday afternoon should also expect heavy traffic. The best time to travel is early in the morning before 10:00 AM on both Tuesday and Wednesday. Thanksgiving Day, November 28th, is expected to have minimal traffic, offering a rare opportunity for smooth driving. Drivers should stay updated with traffic apps and local news to navigate the busy roads efficiently.