Yes, you can lose money applying a fungicide

Should you apply a fungicide to corn? Although it sounds cliché, it depends.

Fungicide applications curbed disease and protected yield potential when applied to a disease-susceptible hybrid in a 2025 trial conducted by Iowa State University and Wyffels Hybrids.

However, fungicide applications on a disease-resistant hybrid showed little or no yield response in the same trial. This occurred under extreme southern rust pressure — the worst since 1999 in Iowa…

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