University of Wisconsin-Madison professors, Jane Paulsen and Michael Newton discovered that two proteins decline in the human brain as Huntington disease develops, furthering improvements for treatments of the disease.
Huntington’s disease (HD) is a rare, genetic disease that causes neurons in the brain to degenerate over time, affecting a person’s movement, cognition and overall quality of life.
Currently, there is no cure for the disease, which typically develops in patients in their 30s and 40s, but symptoms can be treated with different medications. Cases diagnosed in patients younger than 20 are considered juvenile Huntington’s disease and account for 5-10% of all cases…