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The Seafood Shack, a local chain specializing in po’boys, crab boils and fried catfish, is again poised for growth, with plans to open a new location in a former tavern on Milwaukee’s South Side.
Owner Tyseria Griffin recently submitted a proposal for The Seafood Shack Cocktail Lounge at 3954 S. Howell Ave. The building was previously home to Pat’s Niche Pub and Grub, which closed in 2022. A college student-focused cafe, Precious Vibes, was later slated for the space, but never came to fruition. Most recently, Miss Cherrie’s Childcare Center explored plans for the site.
Its incoming tenant would expand both the neighborhood’s food scene and The Seafood Shack’s local footprint, which has fluctuated in recent years. The business’s Wauwatosa location shuttered in March 2024, followed by its South Milwaukee flagship in June 2025. An East Side outlet at 2336 N. Farwell Ave. remains open…