St. Luke’s Unveils $252 Million Heart Hospital at Anderson Campus

The project expands the Anderson Campus’ capacity for cardiovascular care while consolidating a broad range of specialized services within a purpose-built facility. The hospital will include four dedicated heart operating rooms, one hybrid operating room and 10 advanced interventional suites supporting cardiac catheterization, electrophysiology and interventional radiology. | Photo Credit: St. Lukes Univeristy Health Network Inc.

  • $252 million investment: The new St. Luke’s Heart Hospital represents the largest construction project in St. Luke’s University Health Network’s history.
  • 355,000 square feet of space: The five-story facility will significantly expand the St. Luke’s Anderson Campus in Bethlehem, Pennsylvania, adding 140 beds.
  • Purpose-built for cardiovascular care: The hospital will include four heart operating rooms, a hybrid operating room, 10 interventional suites, a dedicated cardiac intensive care unit and advanced imaging and life-support capabilities.
  • Designed around clinical operations: The facility incorporates dedicated staff circulation routes, expanded support spaces and a rooftop helipad to facilitate efficient patient care and emergency access.
  • Opening in October 2026: The Heart Hospital is scheduled to open this fall, expanding St. Luke’s cardiovascular services while adding educational and research opportunities, including a cardiac fellowship program.

BETHLEHEM, Pa. — St. Luke’s University Health Network is preparing to open a new heart hospital at its Anderson Campus in October, adding 140 beds and nearly doubling the size of the campus.

The $252 million St. Luke’s Heart Hospital represents the largest construction project in the health system’s more than 150-year history, both by investment and square footage. The five-story facility encompasses approximately 355,000 square feet and was constructed entirely with American steel. Construction began in 2024 and employed hundreds of skilled workers.

The project expands the Anderson Campus’ capacity for cardiovascular care while consolidating a broad range of specialized services within a purpose-built facility. The hospital will include four dedicated heart operating rooms, one hybrid operating room and 10 advanced interventional suites supporting cardiac catheterization, electrophysiology and interventional radiology…

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